Kentucky forced 16 turnovers and outscored Duke 18-4 in fast-break points. Jamal Murray scored 11 of his 16 points in the second half, and Isiah Briscoe added 12 points as the Wildcats (3-0) placed four players in double figures.
Amile Jefferson led the Blue Devils (2-1) with 16 points and 15 rebounds, and Marshall Plumlee finished with 12 points, 10 rebounds and six blocked shots.
Grayson Allen, who scored 54 points in Duke’s first two games, was held to six points on 2-for-11 shooting. He got his first basket on a 3-pointer from the corner with 12:08 left in the second half.