| All-Time Winning Streaks | |
| Overall | |
| No. Began | Ended |
| 38 Nov. 14, 2014 vs. Grand Canyon, 85-45 | April 4, 2015 vs. Wisconsin, 64-71 |
| 32 Dec. 5, 1953 vs. Temple, 86-59 | Jan. 8, 1955 vs. Georgia Tech, 58-59 |
| 27 Dec. 2, 1995 vs. Indiana, (N) 89-82 | Mar. 10, 1996 vs. Mississippi State, (N) 73-84 |
| 26 Jan. 28, 1946 vs. Georgia Tech, 54-26 | Dec. 30, 1946 vs. Oklahoma State, (N) 31-37 |
| 26 Dec. 30, 2002 vs. Tennessee State, 115-87 | Mar. 29, 2003 vs. Marquette, (N) 69-83 |
| 25 Feb. 27, 1965 vs. Tennessee, 61-60 | Mar. 5, 1966 at Tennessee, 62-69 |
| 24 Feb. 6, 1933 vs. Mexico, 81-22 | Feb. 24, 1934 vs. Florida, (N) 32-38 |
| 24 Dec. 17, 2011 vs. Chattanooga, 87-62 | March 11, 2012 vs. Vanderbilt, (N) 64-71 |
| 23 Jan. 2, 1952 vs. Ole Miss, 116-58 | Mar. 22, 1952 vs. St. John’s, (N) 57-64 |
| 21 Jan. 11, 1949 vs. Bowling Green, (N) 63-61 | Mar. 31, 1949 vs. Loyola, Chicago, (N) 56-67 |
| 21 Dec. 30, 1950 vs. Syracuse, (N) 69-59 | Mar. 3, 1951 vs. Vanderbilt, (N) 57-61 |
| 19 Nov. 13, 2009 vs. Morehead State, 75-59 | Jan. 26, 2010 at South Carolina, 62-68 |
| 18 Feb. 5, 1948 at Alabama, 41-31 | Mar. 31, 1948 vs. Phillips Oilers, (N) 49-53 |
| 16 Mar. 1, 1958 at Tennessee, 77-66 | Jan. 6, 1959 at Vanderbilt, 66-75 |
| 16 Dec. 11, 1961 vs. St. Louis, 86-77 | Feb. 12, 1962 vs. Mississippi State, 44-49 |
| 16 Mar. 15, 1969 vs. Miami, Ohio, (N) 72-71 | Jan. 31, 1970 at Vanderbilt, 81-87 |
| 16 Feb. 21, 1976 vs. Florida, 96-89 | Dec. 18, 1976 vs. Utah, 68-70 |
| 16 Feb. 13, 1978 at Ole Miss, 64-52 | Dec. 16, 1978 at Indiana, 67-68 |
| Single Season | |
| No. Began | Ended |
| 38 Nov. 14, 2014 vs. Grand Canyon, 85-45 | April 4, 2015 vs. Wisconsin, 64-71 |
| 27 Dec. 2, 1995 vs. Indiana, (N) 89-82 | Mar. 10, 1996 vs. Mississippi State, (N) 73-84 |
| 26 Dec. 30, 2002 vs. Tennessee State, 115-87 | Mar. 29, 2003 vs. Marquette, (N) 69-83 |
| *25 Dec. 5, 1953 vs. Temple, 86-59 | Mar. 1, 1954 at Alabama, 68-43 |
| 24 Dec. 17, 2011 vs. Chattanooga, 87-62 | March 11, 2012 vs. Vanderbilt, (N) 64-71 |
| 23 Jan. 2, 1952 vs. Ole Miss, (N) 116-58 | Mar. 22, 1952 vs. St. John’s, (N) 57-64 |
| 23 Dec. 1, 1965 vs. Hardin-Simmons, 83-55 | Mar. 5, 1966 at Tennessee, 62-69 |
| 21 Jan. 11, 1949 vs. Bowling Green, (N) 63-61 | Mar. 14, 1949 vs. Loyola, Chicago, (N) 56-67 |
| 21 Dec. 30, 1950 vs. Syracuse, (N) 69-59 | Mar. 3, 1951 vs. Vanderbilt, (N) 57-61 |
| Homecourt | |
| No. Began | Ended |
| **129 Jan. 4, 1943 vs. Ft. Knox, 64-30 | Jan. 8, 1955 vs. Georgia Tech, 58-59 |
| ^55 Mar. 17, 2009 vs. UNLV, 70-60 | Dec. 1, 2012 vs. Baylor, 64-55 |
| 42 March 4, 2014 vs. Alabama | Dec. 3, 2016 vs. UCLA, 97-92 |
| 39 Jan. 10, 1933 vs. South Carolina, 44-36 | Feb. 22, 1936 vs. Creighton, 29-31 |
| 33 Jan. 29, 1992 vs. Ole Miss, 96-78 | Feb. 9, 1994 vs Arkansas, 82-90 |
| 30 Dec. 1, 1980 vs. E. Tennessee State, 62- | 57 Mar. 6, 1982 vs. Alabama, 46-48 |
| 28 Dec. 21, 1957 vs. Minnesota, 78-58 | Dec. 19, 1959 vs. West Virginia, 70-79 |
| 28 Dec. 20, 1968 vs. Michigan, 112-104 | Dec. 19, 1970 vs. Purdue, 83-89 |
| 27 Jan. 11, 1930 vs. Creighton, 25-21 | Feb. 20, 1932 vs. Vanderbilt, 31-32 |
| 27 Feb. 18, 1995 vs. Florida, 87-77 | Mar. 2, 1997 vs. South Carolina, 66-72 |
| 26 Jan. 22, 1977 vs. LSU, 87-72 | Dec. 22, 1978 vs. Texas A&M, 69-73 |
| 24 Feb. 28, 1985 vs. Tennessee, 92-67 | Jan. 7, 1987 vs. Alabama, 55-69 |
| Biggest Wins | |||||
| Margin | Score | Opponent | Site | Date | |
| 1 | 77 | 143-66 | Georgia | Louisville, Ky. | Feb. 27, 1956 |
| 2 | 74 | 124-50 | Tennessee-Martin | Lexington, Ky. | Nov. 26, 1994 |
| 3 | 72 | 90-18 | Western Ontario | Lexington, Ky. | Dec. 10, 1949 |
| 72 | 96-24 | Wabash | Lexington, Ky. | Dec. 28, 1946 | |
| 5 | 69 | 98-29 | Vanderbilt | Louisville, Ky. | Feb. 27, 1947 |
| 69 | 75-6 | Arkansas State | Lexington, Ky. | Jan. 8, 1945 | |
| 69 | 81-12 | Oglethorpe | Lexington, Ky. | Dec. 13, 1934 | |
| 8 | 66 | 84-18 | Auburn | Louisville, Ky. | Feb. 28, 1947 |
| 9 | 65 | 83-18 | Texas A&M | Lexington, Ky. | Dec. 14, 1946 |
| 10 | 64 | 96-32 | Morehead State | Lexington, Ky. | Dec. 16, 1995 |
| 11 | 62 | 106-44 | Vanderbilt | Lexington, Ky. | Mar. 5, 2003 |
| 12 | 61 | 101-40 | Tennessee | Lexington, Ky. | Mar. 12, 1993 |
| Biggest Losses | |||||
| Margin | Score | Opponent | Site | Date | |
| 1 | -70 | 17-87 | Central | Danville, Ky. | Jan. 28, 1910 |
| 2 | -55 | 95-150 | Kansas | Lawrence, Kan. | Dec. 9, 1989 |
| 3 | -47 | 10-57 | Wabash | Crawfordsville, Ind. | Jan. 6, 1925 |
| 4 | -42 | 9-51 | Central | Danville, Ky. | Mar. 11, 1910 |
| 5 | -41 | 52-93 | Vanderbilt | Nashville, Tenn. | Feb. 12, 2008 |
| -41 | 11-52 | Rose Polytechnic | Terre Haute, Ind. | Feb. 10, 1910 | |
| 7 | -39 | 50-89 | City College of New York | New York, N.Y. | Mar. 14, 1950 |
| 8 | -38 | 10-48 | Cincinnati | Lexington, Ky. | Dec. 18, 1926 |
| 9 | -37 | 17-54 | Christ Church, Cin. | Cincinnati, Ohio | Feb. 15, 1906 |
| 10 | -35 | 41-76 | LSU | Lexington, Ky. | Jan. 18, 1987 |
* UK registered 25 wins during its undefeated season of 1953-54. The team declined a bid to the NCAA Tournament.
** NCAA record
^ Win streak began at Memorial Coliseum due to scheduling conflict at Rupp Arena.