| Date | Opponent | Result | Home / Away | Time | Location | Television |
| Nov. 3 | CALIFORNIA ALL-STARS | W 103 – 74 | H | 7:30 p.m. | Lexington, KY | UKTV Delay |
| Nov. 11 | AUSTRALIAN ALL-STARS | W 88 – 74 | H | 8 p.m. | Lexington, KY | UKTV Live |
| Nov. 17 | EASTERN KENTUCKY | W 99 – 64 | H | 8 p.m. | Lexington, KY | UKTV Live |
| Nov. 19 | MERCER | W 82 – 51 | H | 8 p.m. | Lexington, KY | UKTV Live |
| Nov. 23 | Wright State | W 97 – 75 | (1) | 8 p.m. | Cincinnati, OH | UKTV Live |
Puerto Rico Shootout | ||||||
| Nov. 26 | Colorado | W 64 – 52 | (2) | Bayamone, Puerto Rico | ||
| Nov. 27 | Pittsburgh | L 56 – 68 | (2) | Bayamone, Puerto Rico | ||
| Nov. 28 | UCLA | W 66 – 62 | (2) | Bayamone, Puerto Rico | ||
Great 8 | ||||||
| Dec. 1 | Kansas | W 63 – 45 | (3) | 9:30 p.m. | Chicago, IL | ESPN |
| Dec. 5 | MIAMI, Fla. | W 74 – 65 | H | 3:45 p.m. | Lexington, KY | CBS |
| Dec. 8 | Indiana | W 70 – 61 OT | (4) | 7:30 p.m. | Louisville, KY | ESPN |
| Dec. 12 | MARYLAND | W 103 – 91 | H | 8:30 p.m. | Lexington, KY | ESPN |
Delta Airlines Classis | ||||||
| Dec. 19 | Georgia Tech | W 80 – 39 | (5) | Atlanta, GA | ||
Jimmy V Classic | ||||||
| Dec. 22 | Duke at Jimmy V Classic | L 60 – 71 | (6) | 9 p.m. N4 | East Rutherford, NJ | ESPN |
| Dec. 26 | Louisville | L 74 – 83 | A | 1 p.m. | Louisville, KY | CBS |
| Dec. 29 | TENNESSEE STATE | W 97 – 47 | H | 8 p.m. | Lexington, KY | UKTV Live |
| Jan. 2 | FLORIDA | W 93 – 58 | H | 4 p.m. | Lexington, KY | JP |
| Jan. 5 | South Carolina | W 68 – 61 | A | 9:30 p.m. | Columbia, SC | ESPN |
| Jan. 9 | Vanderbilt | W 73 – 57 | A | 6:30 p.m. | Nashville, TN | FSS |
| Jan. 12 | TENNESSEE | L 46 – 47 | H | 9:30 p.m. | Lexington, KY | ESPN |
| Jan. 16 | Ole Miss | W 63 – 57 | A | 3 p.m. | Oxford, MS | ABC |
| Jan. 20 | AUBURN | W 72 – 62 | H | 8 p.m. | Lexington, KY | JP |
| Jan. 23 | MISSISSIPPI STATE | W 76 – 49 | H | 1 p.m. | Lexington, KY | UKTV Delay |
| Jan. 26 | Georgia | W 91 – 83 OT | A | 9:30 p.m. | Athens, GA | ESPN |
| Jan. 30 | LSU | W 86 – 62 | H | 3 p.m. | Lexington, KY | JP |
| Feb. 4 | Florida | L 68 – 75 | A | 7:30 p.m. | Gainesville, FL | ESPN |
| Feb. 6 | Alabama | L 58 – 62 | A | 3 p.m. | Tuscaloosa, AL | JP |
| Feb. 13 | SOUTH CAROLINA | W 74 – 40 | H | 4 p.m. | Lexington, KY | JP |
| Feb. 17 | GEORGIA | W 92 – 71 | H | 8 p.m. | Lexington, KY | JP |
| Feb. 20 | Arkansas | L 70 – 74 | A | 1 p.m. | Fayetteville, AR | CBS |
| Feb. 24 | VANDERBILT | W 88 – 63 | H | 8 p.m. | Lexington, KY | JP |
| Feb. 28 | Tennessee | L 61 – 68 | A | Noon | Knoxville, TN | CBS |
SEC Tournament | ||||||
| Mar. 5 | Ole Miss | W 83 – 73 | (7) | 7:30 p.m. | Atlanta, GA | JP |
| Mar. 6 | Auburn | W 69 – 57 | (7) | 1:00 p.m. | Atlanta, GA | JP |
| Mar. 7 | Arkansas | W 76 – 63 | (7) | 12:30 p.m. | Atlanta, GA | CBS |
NCAA Tournament | ||||||
| Mar. 12 | New Mexico State | W 82 – 60 | (8) | 10:15 p.m. | New Orleans, LA | CBS |
| Mar. 14 | Kansas | W 92 – 88 OT | (8) | 4:55 p.m. | New Orleans, LA | CBS |
| Mar. 19 | Miami (OH) | W 58 – 43 | (9) | 10:15 p.m. | St. Louis, MO | CBS |
| Mar. 21 | Michigan State | L 66 – 73 | (9) | 5:00 p.m. | St. Louis, MO | CBS |
White = Away Game
Silver = Home Game
1 = Cincinnati, OJ
2 = Puerto Rico Shootout, Bayamone, Puerto Rico
3 = Great 8, Chicago (United Center)
4 = Freedom Hall, Louisville, KY
5 = Delta Airlines Classic, Atlanta (Georgia Dome)
6 = Jimmy V Classic, East Rutherford, N.J. (Meadowlands)
7 = SEC Tournament, Atlanta, GA
8 = NCAA Tournament, New Orleans, LA
9 = NCAA Tournament, St. Louis, MO