| Date | Opponent | Result | Home / Away | Time | Location | Television |
| Nov. 11 | COURT AUTHORITY (Exh.) |
W 86 – 62 | H | 7:30 p.m. | Lexington | UKTV-t |
| Nov. 18 | AUSTRALIAN NATIONAL (Exh.) |
W 91 – 63 | H | 8 p.m. | Lexington | UKTV |
| Nov. 20 | MOREHEAD STATE |
W 88 – 49 | H | 8 p.m. | Lexington | UKTV |
Maui Classic |
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| Nov. 24 | George Washington | W 70 – 55 | (1) | TBA | Hawaii | ESPN |
| Nov. 25 | Arizona | L 74 – 89 | (1) | TBA | Hawaii | ESPN |
| Nov. 26 | Missouri | W 77 – 55 | (1) | TBA | Hawaii | ESPN |
Premier Classic |
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| Nov. 29 | Clemson | W 76 – 61 | (2) | 7:30 | Phoenix | FOX |
Great 8 |
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| Dec. 3 | Purdue | W 89 – 75 | (3) | 9:30 p.m. | Chicago | ESPN |
| Dec. 6 | Indiana | W 75 – 72 | (4) | 3:45 p.m. | Indianapolis | CBS |
| Dec. 10 | Canisius |
W 81 – 54 | A | TBA | Buffalo, N.Y. | UKTV |
| Dec. 13 | GEORGIA TECH |
W 85 – 71 | H | Noon | Lexington | ESPN |
| Dec. 20 | TULSA |
W 74 – 53 | H | 7:30 p.m. | Lexington | ESPN |
| Dec. 23 | AMERICAN |
W 75 – 52 | H | 8 p.m. | Lexington | UKTV |
| Dec. 27 | LOUISVILLE |
L 76 – 79 | H | 4 p.m. | Lexington | CBS |
| Dec. 30 | Ohio U. | W 95 – 58 | A | 7 p.m. | Athens, Ohio | UKTV |
| Jan. 3 | VANDERBILT |
W 71 – 62 | H | 1 p.m. | Lexington | UKTV-t |
| Jan. 6 | Georgia | W 90 – 79 | A | 9:30 p.m. | Athens, Ga. | ESPN |
| Jan. 10 | Mississippi State |
W 77 – 71 | A | 4 p.m. | Starkville, Miss. | JP |
| Jan. 13 | SOUTH CAROLINA |
W 91 – 70 | H | 9:30 p.m. | Lexington | ESPN |
| Jan. 17 | ARKANSAS |
W 80 – 77 OT | H | 4 p.m. | Lexington | CBS |
| Jan. 21 | Alabama | W 70 – 67 | (5) | 7:30 p.m. | Louisville | UKTV-t |
| Jan. 24 | Tennessee |
W 85 – 67 | A | 7:30 p.m. | Knoxville, Tenn. | UKTV-t |
| Jan. 27 | Vanderbilt |
W 63 – 61 | A | 9:30 p.m. | Nashville, Tenn. | ESPN |
| Feb. 1 | FLORIDA |
L 78 – 86 | H | 3:30 p.m. | Lexington | ABC |
| Feb. 4 | LSU | W 63 – 61 | A | 8 p.m. | Baton Rouge, La. | JP |
| Feb. 8 | Villanova |
W 79 – 63 | A | 1 p.m. | Philadelphia | CBS |
| Feb. 11 | TENNESSEE |
W 80 – 74 | H | 8 p.m. | Lexington | JP |
| Feb. 14 | OLE MISS |
L 64 – 73 | H | 12:30 p.m. | Lexington | JP |
| Feb. 18 | Florida | W 79 – 54 | A | 8 p.m. | Gainesville, Fla. | JP |
| Feb. 22 | GEORGIA |
W 85 – 74 | H | 1 p.m. | Lexington | JP |
| Feb. 25 | Auburn | W 83 – 58 | A | 8 p.m. | Auburn, Ala. | JP |
| Feb. 28 | South Carolina |
W 69 – 57 | A | 1 p.m. | Columbia, S.C. | CBS |
SEC Tournament |
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| Mar. 6 | Alabama | W 82 – 71 | (6) | TBA | Atlanta | TBA |
| Mar. 7 | Arkansas | W 99 – 74 | (6) | TBA | Atlanta | TBA |
| Mar. 8 | South Carolina | W 86 – 56 | (6) | TBA | Atlanta | TBA |
NCAA Tournament |
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| Mar. 13 | South Carolina State | W 82 – 67 | (7) | TBA | Atlanta | TBA |
| Mar. 15 | St. Louis | W 88 – 61 | (7) | TBA | Atlanta | TBA |
| Mar. 20 | UCLA | W 94 – 68 | (8) | TBA | St. Petersburg, FL | TBA |
| Mar. 22 | Duke | W 86 – 84 | (8) | TBA | St. Petersburg, FL | TBA |
NCAA FInal Four |
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| Mar. 28 | Stanford | W 86 – 85 OT | (9) | TBA | San Antonio, TX | TBA |
NCAA Championship |
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| Mar. 30 | Utah | W 78 – 69 | (10) | TBA | San Antonio, TX | TBA |
White = Away Game
Silver = Home Game
1 = Maui Classic, Hawaii
2 = Premier Classic, Phoenix, AZ
3 = Great 8, Chicago, IL
4 = Indianapolis, IN
5 = Freedom Hall, Louisville, KY
6 = SEC Tournament, Atlanta, GA
7 = NCAA Tournament 1st and 2nd Rounds, Atlanta, GA
8 = NCAA Tournament Regional Semi-finals and Finals, St. Petersburg, FL
9 = NCAA Tournament Final Four, San Antonio, TX
10 = NCAA Tournament Championship, San Antonion, TX